Augenarzt FMH, FEBO
Spez. Ophthalmochirurgie

Frau Dr. Zandi hat an der Charité in Berlin studiert und promoviert und war dann während fast fünf Jahren an der renommierten Harvard Medical School in Boston, USA tätig. Seit 2011 ist sie in der Schweiz und war zunächst am Universitätsspital in Genf tätig, bevor sie zwischen 2013 und 2019 an der Augenklinik am Lindenhofspital in Bern bei Prof. Garweg ihre chirurgische Ausbildung mit Schwerpunkt Cataract-Chirurgie absolvierte. Seit 2019 ist Frau Dr. Zandi als Oberärztin am Inselspital Bern tätig. Sie besitzt den eidgenössischen Facharzttitel für Ophthalmologie und Ophthalmochirurgie.

Dank ihrer exzellenten Ausbildung und Erfahrung in der chirurgischen Augenheilkunde können wir unser Behandlungsspektrum auch im chirurgischen Bereich ausweiten.

Sprachen: Deutsch, Englisch, Französisch, Spanisch

Publikationen:

• Zandi, S., Freiberg, F., Vaclavik, V., Pfister, IB, Traine, PG, Kaya, C., Michels, S., & Garweg, JG (2020). Morphological Reconstitution and Persistent Changes After Intravitreal Ocriplasmin for Vitreomacular Traction and Macular Hole. Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 36(2), 126–132.

• Traine PG, Pfister IB, Zandi S, Spindler J, Garweg JG. Long-term Outcome of Intravitreal Aflibercept Treatment for Neovascular Age-Related Macular Degeneration Using a „Treat-and-Extend“ Regimen. Ophthalmol Retina. 2019 May;3(5):393-399.
• Zandi S, Pfister IB, Traine PG, Tappeiner C, Despont A, Rieben R, Skowronska M, Garweg JG. Biomarkers for PVR in rhegmatogenous retinal detachment. PLoS One. 2019 Apr 3;14(4):e0214674.
• Garweg JG, Zandi S, Pfister I, Rieben R, Skowronska M, Tappeiner C. Cytokine profiles of phakic and pseudophakic eyes with primary retinal detachment. Acta Ophthalmol. 2018 Dec 18. doi: 10.1111/aos.13998. [Epub ahead of print]
• Spindler J, Zandi S, Pfister IB, Gerhardt C, Garweg JG. Cytokine profiles in the aqueous humor and serum of patients with dry and treated wet age-related macular degeneration.PLoS One. 2018 Aug 29;13(8):e0203337.
• Ahmadieh H, Nourinia R, Hafezi-Moghadam A, Sabbaghi H, Nakao S, Zandi S, Yaseri M, Tofighi Z, Akbarian S. Intravitreal injection of a Rho-kinase inhibitor (fasudil) combined with bevacizumab versus bevacizumab monotherapy for diabetic macular oedema: a pilot randomised clinical trial. Br J Ophthalmol. 2018 Aug 27. pii: bjophthalmol-2018-312244.
• Zandi S, Bodaghi B, Garweg JG.Review for Disease of the Year: Treatment of ViralAnterior Uveitis: A Perspective.Ocul Immunol Inflamm. 2018 Aug 10:1-8.
• Nakao S, Zandi S, Sun D, Hafezi-Moghadam A. Cathepsin B-mediated CD18 shedding regulates leukocyte recruitment from angiogenic vessels.FASEB J. 2018 Jan;32(1):143-154.
• Zandi S, Lereuil T, Freiberg F, Pfau M, Pfister IB, Gerhardt C, Michels S, Kodjikian L, Garweg JG. Long- Term Intravitreal Dexamethasone Treatment in Eyes with Pretreated Chronic Diabetic Macular Edema. J Ocul Pharmacol Ther. 2017 Oct;33(8):620-628.
• Garweg JG, Zandi S, Pfister IB, Skowronska M, Gerhardt C. Comparison of cytokine profiles in the aqueous humor of eyes with pseudoexfoliation syndrome and glaucoma. PLoS One. 2017 Aug 10;12(8):e0182571.
• Nourinia R, Nakao S, Zandi S, Safi S, Hafezi-Moghadam A, Ahmadieh H.ROCK inhibitors for the treatment of ocular diseases. Br J Ophthalmol. 2017 Aug 9. pii: bjophthalmol-2017-310378.
• Garweg JG, Zandi S, Gerhardt C, Pfister IB. Isoforms of TGF-β in the aqueous humor of patients with pseudoexfoliation syndrome and a possible association with the long- term stability of the capsular bag after cataract surgery.Graefes Arch Clin Exp Ophthalmol. 2017 Sep;255(9):1763-1769.
• Frimmel S, Zandi S, Sun D, Zhang Z, Schering A, Melhorn MI,  Nakao S, Hafezi-Moghadam A. Molecular Imaging of Retinal Endothelial Injury in Diabetic Animals. J Ophthalmic Vis Res. 2017 Apr-Jun;12(2):175-182.
• Zandi S,Weisskopf F, Garweg JG, Pfister IB, Pruente C, Sutter F, Hatz K. Pre-Existing RPE Atrophy and Defects in the External Limiting Membrane Predict Early Poor Visual Response to Ranibizumab in Neovascular Age-Related Macular Degeneration. Ophthalmic Surg Lasers Imaging Retina. 2017 Apr 1;48(4):326-332
• Zandi S, Tappeiner C, Pfister IB, Despont A, Rieben R, Garweg JG. Vitreal Cytokine Profile Differences Between Eyes With Epiretinal Membranes or Macular Holes.Invest Ophthalmol Vis Sci. 2016                   Nov1;57(14):6320-6326.
• Garweg JG, Zandi S. Impact of treatment on long-term visual function in retinal vein occlusion- response to the comment on: retinal vein occlusion and the use of a dexamethasone intravitreal implant (Ozurdex®) in its treatment.Graefes Arch Clin Exp Ophthalmol. 2016 Dec;254(12):2479-2480.
• Garweg JG, Baglivo E, Freiberg FJ, Pfau M, Pfister IB, Michels S, Zandi S. Response of  Postoperative and Chronic Uveitic Cystoid Macular Edema to a Dexamethasone-Based Intravitreal Implant (Ozurdex).J Ocul Pharmacol Ther. 2016 Sep;32(7):442-50.
• Garweg JG, Zandi S. Retinal vein occlusion and the use of a dexamethasone intravitreal implant (Ozurdex®) in its treatment. Graefes Arch Clin Exp Ophthalmol. 2016 Jul;254(7):1257-65.
• Taher M, Nakao S, Zandi S, Melhorn MI, Hayes KC, Hafezi-Moghadam A. Phenotypic transformation of intimal and adventitial lymphatics in atherosclerosis: a regulatory role for soluble VEGF receptor 2.FASEB J. 2016 Jul;30(7):2490-9.
• Sanjari N, Pakravan M, Nourinia R, Esfandiari H, Hafezi-Moghadam A, Zandi S, Nakao S, Shah- Heidari MH, Jamali A, Yaseri M, Ahmadieh H. Intravitreal Injection of a Rho-Kinase Inhibitor (Fasudil) for Recent-Onset Nonarteritic Anterior Ischemic Optic Neuropathy.J Clin Pharmacol. 2016   Jun;56(6):749-53.
• Zandi S, Nakao S, Chun KH, Fiorina P, Sun D, Arita R, Zhao M, Kim E, Schueller O, Campbell S, Taher M, Melhorn MI, Schering A, Gatti F, Tezza S, Xie F, Vergani A, Yoshida S, Ishikawa K, Yamaguchi M, Sasaki F, Schmidt-Ullrich R, Hata Y, Enaida H, Yuzawa M, Yokomizo T, Kim YB, Sweetnam P, Ishibashi T, Hafezi-Moghadam A. ROCK-isoform-specific polarization of macrophages associated with age- related macular degeneration. Cell Rep. 2015 Feb 24;10(7):1173-86.
• Richoz O, KlingS, Zandi S, Hammer A, Spoerl E, Hafezi F. A constant-force technique to measure corneal biomechanical  changes after collagen cross-linking.  PLoS One. 2014 Aug 27;9(8):e105095.
• Sun D, Nakao S, Xie F, Zandi S, Bagheri A, Kanavi MR, Samiei S, Soheili Z, Frimmel S, Zhang Z, Ablonczy Z, Ahmadieh H, Hafezi-Moghadam A. Molecular imaging reveals elevated VEGFR-2 expression in retinal capillaries in diabetes: A novel biomarker for early diagnosis. FASEB J. 2014 Jun 5pii: fj.14-251934. [Epub ahead of print]
• Nourinia R, Ahmadieh H, Shahheidari MH, Zandi S, Nakao S, Hafezi-Moghadam A. Intravitreal fasudil combined with bevacizumab for treatment of refractory diabetic macular edema; a pilot study. J Ophthalmic Vis Res. 2013 Oct;8(4):337-40.
• Retinopathy in a novel model of metabolic syndrome and type 2 diabetes: new insight on the inflammatory paradigm. Noda K, Nakao S, Zandi S, Sun D, Hayes KC, Hafezi-Moghadam A. FASEB J. 2014 May;28(5):2038-46.
• Nakao S, Zandi S, Kohno R, Sun D, Nakama T, Ishikawa K, Yoshida S, Enaida H, Ishibashi T, Hafezi-Moghadam A. Lack of lymphatics and lymph node-mediated immunity in choroidal neovascularization. Invest Ophthalmol Vis Sci. 2013 Jul 3;54(6):3830-6.
• Nakao S, Zandi S, Lara-Castillo N, Taher M, Ishibashi, A.Hafezi-Moghadam. Larger therapeutic window for steroid vs VEGF-A inhibitor in inflammatory angiogenesis: Surprisingly similar impact on leukocyte infiltration. Invest Ophthalmol Vis Sci. 2012 Jun 5;53(7):3296-302.
• Nakao S, Zandi S, Faez S, Kohno R, Hafezi-Moghadam A Discontinuous LYVE-1 expression in corneal limbal lymphatics: dual function as microvalves and immunological hot spots. FASEB J. 2012 Feb;26(2):808-17.
• Nakao S, Noda K, Zandi S, Sun D, Taher M, Schering A, Xie F, Mashima Y, Hafezi-Moghadam VAP-1-Mediated M2 Macrophage Infiltration Underlies IL-1β- but Not VEGF-A-Induced Lymph- and Angiogenesis. Am J Pathol. 2011 Apr;178(4):1913-21.
• Garland RC, Sun D, Zandi S, Xie F, Faez S, Tayyari F, Frimmel SA, Schering A, Nakao S, Hafezi-Moghadam A. Noninvasive molecular imaging reveals role of PAF in leukocyte-endothelial interaction in LPS-induced ocular vascular injury FASEB J. 2011 Apr;25(4):1284-94.
• Nakao S, Zandi S, Hata Y, Kawahara S, Arita R, Schering A, Sun D, Melhorn MI, Ito Y, Lara-Castillo N, Ishibashi T, Hafezi-Moghadam A. Blood vessel endothelial VEGFR-2 delays lymphangiogenesis: an endogenous trapping mechanism links lymph- and angiogenesis.Blood. 2011 Jan;117(3):1081-90.
• Xie F, Sun D, Schering A, Nakao S, Zandi S, Liu P, Hafezi-Moghadam A. Novel molecular imaging approach for subclinical detection of iritis and evaluation of therapeutic success. Am J Pathol. 2010 Jul;177(1):39-48.
• Matziolis D, Kaeaeb M, Zandi S, Perka C, Greiner S. Surgical treatment of two-part fractures of the proximal humerus: Comparison of fixed-angle plate osteosynthesis and Zifko nails. Injury. Oct;41(10):1041-46.
• Noda K, Melhorn MI, Zandi S, Frimmel S, Tayyari F, Hisatomi T, Almulki L, Pronczuk A, Hayes KC, Hafezi-Moghadam A. An animal model of spontaneous metabolic syndrome: Nile grass rat.FASEB J. 2010 Jul;24(7):2443-53.
• Sun D, Nakao S, Xie F, Zandi S, Schering A, Hafezi-Moghadam A. Superior sensitivity of novel molecular imaging probe: simultaneously targeting two types of endothelial injury markers.FASEB J. 2010 May;24(5):1532-40.
• Lara-Castillo N, Zandi S, Nakao S, Ito Y, Noda K, She H, Ahmed M, Frimmel S, Ablonczy Z, Hafezi-Moghadam A. Atrial natriuretic peptide reduces vascular leakage and choroidal neovascularization. Am J Pathol. 2009 Dec;175(6):2343-50.
• Nakao S, Maruyama K, Zandi S, Melhorn MI, Taher M, Noda K, Nusayr E, Doetschman T, Hafezi-Moghadam A. Lymphangiogenesis and angiogenesis: concurrence and/or dependence? Studies in inbred mouse strains. FASEB J. 2010 Feb;24(2):504-13.
• Noda K, Nakao S, Zandi S, Engelstädter V, Mashima Y, Hafezi-Moghadam A. Vascular adhesion protein-1 regulates leukocyte transmigration rate in the retina during diabetes.Exp Eye Res. 2009 Nov;89(5):774-81.
• Arita R, Hata Y, Nakao S, Kita T, Miura M, Kawahara S, Zandi S, Almulki L, Tayyari F, Schimokawa H, Hafezi-Moghadam A, Ishibashi T. Rho kinase inhibition by fasudil ameliorates diabetes-induced microvascular damage. Diabetes. 2009 Jan;58(1):215-26.
• Noda K, She H, Nakazawa T, Hisatomi T, Nakao S, Almulki L, Zandi S, Miyahara S, Ito Y, Thomas KL, Garland RC, Miller JW, Gragoudas ES, Mashima Y, Hafezi-Moghadam. Vascular Adhesion Protein-1 Blockade Suppresses Choroidal Neovascularization. FASEB J.2008 Aug;22(8):2928-35.
• Skondra D, Noda K, Almulki L, Tayyari F, Frimmel S, Nakazawa T, Kim IK, Zandi S, Thomas KL, Miller JW, Gragoudas ES, Hafezi-Moghadam A. Characterization of Azurocidin as a Permeability Factor in the Retina: Involvement in VEGF-Induced and Early Diabetic Blood-Retinal Barrier Breakdown.Invest Ophthalmol Vis Sci. 2008 Feb;49(2):726-31.
• Miyahara S, Almulki L, Noda K, Nakazawa T, Hisatomi T, Nakao S, Thomas KL, Schering A, Zandi S, Frimmel S, Tayyari F, Garland RC, Miller JW, Gragoudas ES, Masil S, Hafezi-Moghadam A. In vivo imaging of endothelial injury in choriocapillaris during endotoxin-induced uveitis. FASEB J. 2008 Jun;22(6):1973-80.